Chimaerin beta 3 Positive Control peptide (STJ503905)

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STJ503905-5
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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Chimaerin beta 3 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: CHN2
Gene ID: 1124
Uniprot ID: CHIO_HUMAN
Tissue Specificity Highest levels in the brain and pancreas. Also expressed in the heart, placenta, and weakly in the kidney and liver. Expression is much reduced in the malignant gliomas, compared to normal brain or low-grade astrocytomas.
Function GTPase-activating protein for p21-rac. Insufficient expression of beta-2 chimaerin is expected to lead to higher Rac activity and could therefore play a role in the progression from low-grade to high-grade tumors.
Peptide Name Beta-Chimaerin
Beta-Chimerin
Rho Gtpase-Activating Protein 3
Database Links Reactome: R-HSA-9013149
Cellular Localisation Membrane
Peripheral Membrane Protein
Alternative Peptide Names Beta-Chimaerin protein
Beta-Chimerin protein
Rho Gtpase-Activating Protein 3 protein
CHN2 protein
ARHGAP3 protein
BCH protein

Information sourced from Uniprot.org

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