| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Cannabinoid Receptor II Blocking Peptide is synthetically produced from the 300-347 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Cnr2 |
| Gene ID: |
12802 |
| Uniprot ID: |
CNR2_MOUSE |
| Immunogen Region: |
300-347 |
| Immunogen: |
Synthetic peptide taken within amino acid region 300-347 on mouse CB2 Receptor protein common to both CB2L and CB2S. |
| Tissue Specificity | Expressed by cells of hematopoietic origin. Expressed in skin in suprabasal layers and hair follicles, in brain by neurons and glial cells and by osteoblasts, osteocytes, osteoclasts (at protein level). |
| Function | Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis. |
| Peptide Name | Cannabinoid Receptor 2Cb-2Cb2Mcb2 |
| Database Links | Reactome: R-MMU-373076Reactome: -MMU-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionDendritePerikaryonLocalizes To Apical Dendrite Of Pyramidal Neurons |
| Alternative Peptide Names | Cannabinoid Receptor 2 proteinCb-2 proteinCb2 proteinMcb2 proteinCnr2 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
