Anti-ZNF263 antibody (557-607) (STJA0006562)

SKU:
STJA0006562

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Zinc finger protein 263 (557-607) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ZNF263
Gene ID: 10127
Uniprot ID: ZN263_HUMAN
Immunogen Region: 557-607
Specificity: This antibody detects endogenous levels of human ZN263
Immunogen: Synthesized peptide derived from human ZN263 AA range: 557-607
Post Translational Modifications Ubiquitinated, leading to proteasomal degradation.
Function Transcription factor that binds to the consensus sequence 5'-TCCTCCC-3' and acts as a transcriptional repressor. Binds to the promoter region of SIX3 and recruits other proteins involved in chromatin modification and transcriptional corepression, resulting in methylation of the promoter and transcriptional repression. Acts as transcriptional repressor of HS3ST1 and HS3ST3A1 via binding to gene promoter regions.
Protein Name Zinc Finger Protein 263
Zinc Finger Protein Fpm315
Zinc Finger Protein With Krab And Scan Domains 12
Database Links Reactome: R-HSA-212436
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Zinc Finger Protein 263 antibody
Anti-Zinc Finger Protein Fpm315 antibody
Anti-Zinc Finger Protein With Krab And Scan Domains 12 antibody
Anti-ZNF263 antibody
Anti-FPM315 antibody
Anti-ZKSCAN12 antibody

Information sourced from Uniprot.org

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