Tissue Specificity | Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte. |
Post Translational Modifications | Ubiquitinated, leading to proteasomal degradation. |
Function | Transcription factor that binds to the consensus sequence 5'-TCCTCCC-3' and acts as a transcriptional repressor. Binds to the promoter region of SIX3 and recruits other proteins involved in chromatin modification and transcriptional corepression, resulting in methylation of the promoter and transcriptional repression. Acts as a transcriptional repressor of HS3ST1 and HS3ST3A1 via binding to gene promoter regions. |
Protein Name | Zinc Finger Protein 263Zinc Finger Protein Fpm315Zinc Finger Protein With Krab And Scan Domains 12 |
Database Links | Reactome: R-HSA-212436 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Zinc Finger Protein 263 antibodyAnti-Zinc Finger Protein Fpm315 antibodyAnti-Zinc Finger Protein With Krab And Scan Domains 12 antibodyAnti-ZNF263 antibodyAnti-FPM315 antibodyAnti-ZKSCAN12 antibody |
Information sourced from Uniprot.org