• Western blot analysis of various lysates, using ZNF263 rabbit polyclonal antibody (STJ118905) at 1:600 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
  • Immunohistochemistry analysis of paraffin-embedded Human colon using ZNF263 rabbit polyclonal antibody (STJ118905) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Anti-ZNF263 antibody (120-240) (STJ118905)

Anti-ZNF263 antibody (120-240) (STJ118905)

SKU:
STJ118905

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ZNF263 (120-240) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ZNF263
Gene ID: 10127
Uniprot ID: ZN263_HUMAN
Immunogen Region: 120-240
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-240 of human ZNF263 (NP_005732.2).
Immunogen Sequence: QRELGRLRQQVTNHGRGTEV LLEEPLPLETARESPSFKLE PMETERSPGPRLQELLGPSP QRDPQAVKERALSAPWLSLF PPEGNMEDKEMTGPQLPESL EDVAMYISQEEWGHQDPSKR A
Tissue Specificity Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte.
Post Translational Modifications Ubiquitinated, leading to proteasomal degradation.
Function Transcription factor that binds to the consensus sequence 5'-TCCTCCC-3' and acts as a transcriptional repressor. Binds to the promoter region of SIX3 and recruits other proteins involved in chromatin modification and transcriptional corepression, resulting in methylation of the promoter and transcriptional repression. Acts as transcriptional repressor of HS3ST1 and HS3ST3A1 via binding to gene promoter regions.
Protein Name Zinc Finger Protein 263
Zinc Finger Protein Fpm315
Zinc Finger Protein With Krab And Scan Domains 12
Database Links Reactome: R-HSA-212436
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Zinc Finger Protein 263 antibody
Anti-Zinc Finger Protein Fpm315 antibody
Anti-Zinc Finger Protein With Krab And Scan Domains 12 antibody
Anti-ZNF263 antibody
Anti-FPM315 antibody
Anti-ZKSCAN12 antibody

Information sourced from Uniprot.org

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