| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Zinc finger protein 106 (1833-1882 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ZNF106 |
| Gene ID: | 64397 |
| Uniprot ID: | ZN106_HUMAN |
| Immunogen Region: | 1833-1882 aa |
| Specificity: | ZFP106 Polyclonal Antibody detects endogenous levels of ZFP106 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human ZFP106 at the amino acid range 1833-1882 |
| Function | RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism. |
| Protein Name | Zinc Finger Protein 106Zfp-106Zinc Finger Protein 474 |
| Cellular Localisation | NucleusNucleolusNucleus SpeckleColocalizes With Rbm39 In Nuclear SpecklesInhibition Of Rna SynthesisOr Overexpression Of Knop1Induces Translocation From Nuclear Speckles To The Nucleolus |
| Alternative Antibody Names | Anti-Zinc Finger Protein 106 antibodyAnti-Zfp-106 antibodyAnti-Zinc Finger Protein 474 antibodyAnti-ZNF106 antibodyAnti-SH3BP3 antibodyAnti-ZFP106 antibodyAnti-ZNF474 antibody |
Information sourced from Uniprot.org