| Function | Transcriptional factor that binds to the consensus sequence 5'-GTAGAGTGGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas. |
| Protein Name | Zinc Finger Protein With Krab And Scan Domains 3Zinc Finger And Scan Domain-Containing Protein 13Zinc Finger Protein 306Zinc Finger Protein 309Zinc Finger Protein 47 HomologZf47Zfp-47 |
| Database Links | Reactome: R-HSA-212436 |
| Cellular Localisation | NucleusCytoplasmMainly Localizes In The NucleusUnder Starvation Conditions Translocates To The CytoplasmAllowing Expression Of Target Genes Involved In Autophagy And Lysosome Biogenesis/Function |
| Alternative Antibody Names | Anti-Zinc Finger Protein With Krab And Scan Domains 3 antibodyAnti-Zinc Finger And Scan Domain-Containing Protein 13 antibodyAnti-Zinc Finger Protein 306 antibodyAnti-Zinc Finger Protein 309 antibodyAnti-Zinc Finger Protein 47 Homolog antibodyAnti-Zf47 antibodyAnti-Zfp-47 antibodyAnti-ZKSCAN3 antibodyAnti-ZFP47 antibodyAnti-ZNF306 antibodyAnti-ZNF309 antibodyAnti-ZSCAN13 antibody |
Information sourced from Uniprot.org
