| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Zinc finger protein ZFPM2 (921-970 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 IHC-P 1:100-1:300 ELISA 1:10000 IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ZFPM2 |
| Gene ID: | 23414 |
| Uniprot ID: | FOG2_HUMAN |
| Immunogen Region: | 921-970 aa |
| Specificity: | FOG-2 Polyclonal Antibody detects endogenous levels of FOG-2 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the Internal region of human ZFPM2 at the amino acid range 921-970 |
| Post Translational Modifications | Sumoylation reduces transcriptional repression activity. |
| Function | Transcription regulator that plays a central role in heart morphogenesis and development of coronary vessels from epicardium, by regulating genes that are essential during cardiogenesis. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA4, GATA5 and GATA6. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. Also required in gonadal differentiation, possibly be regulating expression of SRY. Probably acts a corepressor of NR2F2. |
| Protein Name | Zinc Finger Protein Zfpm2 Friend Of Gata Protein 2 Fog-2 Friend Of Gata 2 Hfog-2 Zinc Finger Protein 89b Zinc Finger Protein Multitype 2 |
| Database Links | Reactome: R-HSA-9690406 Reactome: R-HSA-983231 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Zinc Finger Protein Zfpm2 antibody Anti-Friend Of Gata Protein 2 antibody Anti-Fog-2 antibody Anti-Friend Of Gata 2 antibody Anti-Hfog-2 antibody Anti-Zinc Finger Protein 89b antibody Anti-Zinc Finger Protein Multitype 2 antibody Anti-ZFPM2 antibody Anti-FOG2 antibody Anti-ZNF89B antibody |
Information sourced from Uniprot.org