| Function | Palmitoyltransferase that catalyzes the addition of palmitate onto protein substrates including the D(2) dopamine receptor DRD2, GSK3B or MAVS. Mediates GSK3B palmitoylation to prevent its AKT1-mediated phosphorylation leading to activation of the STAT3 signaling pathway. Catalyzes also MAVS palmitoylation which promotes its stabilization and activation by inhibiting 'Lys-48'- but facilitating 'Lys-63'-linked ubiquitination. |
| Protein Name | Palmitoyltransferase Zdhhc4Zinc Finger Dhhc Domain-Containing Protein 4Dhhc-4Zinc Finger Protein 374 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinGolgi Apparatus MembraneCell Membrane |
| Alternative Antibody Names | Anti-Palmitoyltransferase Zdhhc4 antibodyAnti-Zinc Finger Dhhc Domain-Containing Protein 4 antibodyAnti-Dhhc-4 antibodyAnti-Zinc Finger Protein 374 antibodyAnti-ZDHHC4 antibodyAnti-ZNF374 antibodyAnti-DC1 antibodyAnti-UNQ5787 antibodyAnti-PRO19576 antibody |
Information sourced from Uniprot.org
