| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ZDHHC4 |
| Gene ID: |
55146 |
| Uniprot ID: |
ZDHC4_HUMAN |
| Immunogen Region: |
110-210 |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 110-210 of human ZDHHC4 (NP_060576.1). |
| Immunogen Sequence: |
VNLFFFTLTCGTNPGIITKA NELLFLHVYEFDEVMFPKNV RCSTCDLRKPARSKHCSVCN WCVHRFDHHCVWVNNCIGAW NIRYFLIYVLTLTASAATVA I |
| Function | Palmitoyltransferase that catalyzes the addition of palmitate onto protein substrates including the D(2) dopamine receptor DRD2, GSK3B or MAVS. Mediates GSK3B palmitoylation to prevent its AKT1-mediated phosphorylation leading to activation of the STAT3 signaling pathway. Catalyzes also MAVS palmitoylation which promotes its stabilization and activation by inhibiting 'Lys-48'- but facilitating 'Lys-63'-linked ubiquitination. |
| Protein Name | Palmitoyltransferase Zdhhc4Zinc Finger Dhhc Domain-Containing Protein 4Dhhc-4Zinc Finger Protein 374 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinGolgi Apparatus MembraneCell Membrane |
| Alternative Antibody Names | Anti-Palmitoyltransferase Zdhhc4 antibodyAnti-Zinc Finger Dhhc Domain-Containing Protein 4 antibodyAnti-Dhhc-4 antibodyAnti-Zinc Finger Protein 374 antibodyAnti-ZDHHC4 antibodyAnti-ZNF374 antibodyAnti-DC1 antibodyAnti-UNQ5787 antibodyAnti-PRO19576 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
