| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ZCWPW1 (389-648) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ZCWPW1 |
| Gene ID: |
55063 |
| Uniprot ID: |
ZCPW1_HUMAN |
| Immunogen Region: |
389-648 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 389-648 of human ZCWPW1 (NP_060454.3). |
| Immunogen Sequence: |
VMKKRRNDCSQKLGVALMMA QEAEQISIQERVNLFGFWSR FNGSNSNGERKDLQLSGLNS PGSCLEKKEKEEELEKEEGE KTDPILPIRKRVKIQTQKTK PRGLGGDAGTADGRGRTLQR KIMKRSLGRKSTAPPAPRMG RKEGQGNSDSDQPGPKKKFK APQSKALAASFSEGKEVRTV PKNLGLSACKGACPSSAKEE PRHREPLTQEAGSVPLEDEA SSDLDLEQLMEDVGRELGQ |
| Tissue Specificity | Testis. |
| Function | Dual histone methylation reader specific for PRDM9-catalyzed histone marks (H3K4me3 and H3K36me3). Facilitates the repair of PRDM9-induced meiotic double-strand breaks (DSBs). Essential for male fertility and spermatogenesis. Required for meiosis prophase I progression in male but not in female germ cells. |
| Protein Name | Zinc Finger Cw-Type Pwwp Domain Protein 1 |
| Cellular Localisation | NucleusChromosome |
| Alternative Antibody Names | Anti-Zinc Finger Cw-Type Pwwp Domain Protein 1 antibodyAnti-ZCWPW1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
