Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-14-3-3 protein theta (196-245 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:5000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
YWHAQ |
Gene ID: |
10971 |
Uniprot ID: |
1433T_HUMAN |
Immunogen Region: |
196-245 aa |
Specificity: |
14-3-3 Theta/Tau Polyclonal Antibody detects endogenous levels of 14-3-3 Theta/Tau protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human 14-3-3 thet/tau at the amino acid range 196-245 |
Post Translational Modifications | Ser-232 is probably phosphorylated by CK1. |
Function | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1. |
Protein Name | 14-3-3 Protein Theta14-3-3 Protein T-Cell14-3-3 Protein TauProtein Hs1 |
Database Links | Reactome: R-HSA-111447Reactome: R-HSA-1445148Reactome: R-HSA-5625740Reactome: R-HSA-5628897Reactome: R-HSA-75035Reactome: R-HSA-9614399Reactome: R-HSA-9735871Reactome: R-HSA-9755779 |
Cellular Localisation | CytoplasmIn NeuronsAxonally Transported To The Nerve Terminals |
Alternative Antibody Names | Anti-14-3-3 Protein Theta antibodyAnti-14-3-3 Protein T-Cell antibodyAnti-14-3-3 Protein Tau antibodyAnti-Protein Hs1 antibodyAnti-YWHAQ antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance