| Host: |
Rabbit |
| Applications: |
WB/IHC/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Threonylcarbamoyl-Amp Synthase is suitable for use in Western Blot, Immunohistochemistry and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Purification: |
Antigen affinity purification |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000, IHC 1:25-1:100 |
| Storage Instruction: |
Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Gene Symbol: |
YRDC |
| Gene ID: |
79693 |
| Uniprot ID: |
YRDC_HUMAN |
| Immunogen: |
Synthetic peptide of human YRDC |
| Tissue Specificity | Ubiquitously expressed. |
| Function | Cytoplasmic and mitochondrial threonylcarbamoyl-AMP synthase required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. Participates in t(6)A37 formation in cytoplasmic and mitochondrial tRNAs. May regulate the activity of some transporters. |
| Protein Name | Threonylcarbamoyl-Amp SynthaseDopamine Receptor-Interacting Protein 3Ischemia/Reperfusion-Inducible Protein HomologHirip |
| Cellular Localisation | CytoplasmMitochondrionCell MembranePeripheral Membrane ProteinA Large Fraction Localizes In The CytoplasmWhereas A Smaller Fraction Is Imported To Mitochondria |
| Alternative Antibody Names | Anti-Threonylcarbamoyl-Amp Synthase antibodyAnti-Dopamine Receptor-Interacting Protein 3 antibodyAnti-Ischemia/Reperfusion-Inducible Protein Homolog antibodyAnti-Hirip antibodyAnti-YRDC antibodyAnti-DRIP3 antibodyAnti-IRIP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
