Anti-YRDC antibody (214-264 aa) (STJ198010)

SKU:
STJ198010
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Threonylcarbamoyl-AMP synthase (214-264 aa) is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: YRDC
Gene ID: 79693
Uniprot ID: YRDC_HUMAN
Immunogen Region: 214-264 aa
Specificity: This antibody detects endogenous levels of human YRDC
Immunogen: Synthesized peptide derived from the human YRDC at the amino acid range 214-264
Function Cytoplasmic and mitochondrial threonylcarbamoyl-AMP synthase required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. Participates in t(6)A37 formation in cytoplasmic and mitochondrial tRNAs. May regulate the activity of some transporters.
Protein Name Threonylcarbamoyl-Amp Synthase
Dopamine Receptor-Interacting Protein 3
Ischemia/Reperfusion-Inducible Protein Homolog
Hirip
Cellular Localisation Cytoplasm
Mitochondrion
Cell Membrane
Peripheral Membrane Protein
A Large Fraction Localizes In The Cytoplasm
Whereas A Smaller Fraction Is Imported To Mitochondria
Alternative Antibody Names Anti-Threonylcarbamoyl-Amp Synthase antibody
Anti-Dopamine Receptor-Interacting Protein 3 antibody
Anti-Ischemia/Reperfusion-Inducible Protein Homolog antibody
Anti-Hirip antibody
Anti-YRDC antibody
Anti-DRIP3 antibody
Anti-IRIP antibody

Information sourced from Uniprot.org

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