Anti-YRDC antibody (214-264 aa) (STJ198010)

SKU:
STJ198010
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-Threonylcarbamoyl-AMP synthase (214-264 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:1000-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:YRDC
Gene ID:79693
Uniprot ID:YRDC_HUMAN
Immunogen:Synthesized peptide derived from the human YRDC at the amino acid range 214-264
Immunogen Region:214-264 aa
Specificity:This antibody detects endogenous levels of human YRDC
Function Cytoplasmic and mitochondrial threonylcarbamoyl-AMP synthase required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. Participates in t(6)A37 formation in cytoplasmic and mitochondrial tRNAs. May regulate the activity of some transporters.
Protein Name Threonylcarbamoyl-Amp Synthase
Dopamine Receptor-Interacting Protein 3
Ischemia/Reperfusion-Inducible Protein Homolog
Hirip
Database Links
Cellular Localisation Cytoplasm
Mitochondrion
Cell Membrane
Peripheral Membrane Protein
A Large Fraction Localizes In The Cytoplasm
Whereas A Smaller Fraction Is Imported To Mitochondria
Alternative Antibody Names Anti-Threonylcarbamoyl-Amp Synthase antibody
Anti-Dopamine Receptor-Interacting Protein 3 antibody
Anti-Ischemia/Reperfusion-Inducible Protein Homolog antibody
Anti-Hirip antibody
Anti-YRDC antibody
Anti-DRIP3 antibody
Anti-IRIP antibody

Information sourced from Uniprot.org