| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Xylosyltransferase 1 (312-362 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
XYLT1 |
| Gene ID: |
64131 |
| Uniprot ID: |
XYLT1_HUMAN |
| Immunogen Region: |
312-362 aa |
| Specificity: |
This antibody detects endogenous levels of XYLT1 at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human XYLT1 at the amino acid range 312-362 |
| Post Translational Modifications | Contains 7 disulfide bonds. N-glycosylated. |
| Function | Catalyzes the first step in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans, such as DCN. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Required for normal embryonic and postnatal skeleton development, especially of the long bones. Required for normal maturation of chondrocytes during bone development, and normal onset of ossification. |
| Protein Name | Xylosyltransferase 1Peptide O-Xylosyltransferase 1Xylosyltransferase IXt-IXylt-I |
| Database Links | Reactome: R-HSA-1971475 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinSecretedDetected Predominantly In The Golgi Apparatus |
| Alternative Antibody Names | Anti-Xylosyltransferase 1 antibodyAnti-Peptide O-Xylosyltransferase 1 antibodyAnti-Xylosyltransferase I antibodyAnti-Xt-I antibodyAnti-Xylt-I antibodyAnti-XYLT1 antibodyAnti-XT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
