| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | XPNPEP2 |
| Gene ID: | 7512 |
| Uniprot ID: | XPP2_HUMAN |
| Immunogen Region: | 22-240 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-240 of human XPNPEP2 (NP_003390.4). |
| Immunogen Sequence: | HTKPVDLGGQDVRNCSTNPP YLPVTVVNTTMSLTALRQQM QTQNLSAYIIPGTDAHMNEY IGQHDERRAWITGFTGSAGT AVVTMKKAAVWTDSRYWTQA ERQMDCNWELHKEVGTTPIV TWLLTEIPAGGRVGFDPFLL SIDTWESYDLALQGSNRQLV SITTNLVDLVWGSERPPVPN QPIYALQEAFTGSTWQEKVS GVRSQMQKHQKVPTAVLLS |
| Tissue Specificity | Expressed in kidney, lung, heart, placenta, liver, small intestine and colon. No expression in brain, skeletal muscle, pancreas, spleen, thymus, prostate, testis and ovary. |
| Post Translational Modifications | N-glycosylated. |
| Function | Membrane-bound metalloprotease which catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. May play a role in the metabolism of the vasodilator bradykinin. |
| Protein Name | Xaa-Pro Aminopeptidase 2Aminoacylproline AminopeptidaseMembrane-Bound Aminopeptidase PMembrane-Bound AppMembrane-Bound AmpMampX-Pro Aminopeptidase 2 |
| Database Links | Reactome: R-HSA-163125 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Xaa-Pro Aminopeptidase 2 antibodyAnti-Aminoacylproline Aminopeptidase antibodyAnti-Membrane-Bound Aminopeptidase P antibodyAnti-Membrane-Bound App antibodyAnti-Membrane-Bound Amp antibodyAnti-Mamp antibodyAnti-X-Pro Aminopeptidase 2 antibodyAnti-XPNPEP2 antibody |
Information sourced from Uniprot.org