| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-XK-related protein 8 (111-161 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
XKR8 |
| Gene ID: |
55113 |
| Uniprot ID: |
XKR8_HUMAN |
| Immunogen Region: |
111-161 aa |
| Specificity: |
This antibody detects endogenous levels of XKR8 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human XKR8 at the amino acid range 111-161 |
| Function | XK-related protein 8, processed form: Phospholipid scramblase that promotes phosphatidylserine exposure on apoptotic cell surface. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment. Required for the clearance of apoptotic cells, such as engulfment of apoptotic germ cells by Sertoli cells, clearance of senescent neutrophils or regulation of bipolar cell numbers in the retina. Has no effect on calcium-induced exposure of phosphatidylserine. Promotes myoblast differentiation and survival. (Microbial infection) Incorporated into Ebola virus-like particles, where its phospholipid scramblase activity is required to promote phosphatidylserine exposure on the surface of viral particles. Externalization of phosphatidylserine on the surface of viral particles is required for uptake by host cells. |
| Protein Name | Xk-Related Protein 8Hxkr8 Cleaved Into - Xk-Related Protein 8 - Processed Form |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytoplasmPerinuclear Region |
| Alternative Antibody Names | Anti-Xk-Related Protein 8 antibodyAnti-Hxkr8 Cleaved Into - Xk-Related Protein 8 - Processed Form antibodyAnti-XKR8 antibodyAnti-XRG8 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
