Name: Anti-WT1 antibody [6F‐H2] (STJ180267)
SKU: STJ180267
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Anti-WT1 antibody [6F‐H2] (STJ180267)

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STJ180267

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Short Description :	Mouse monoclonal WT1 antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:	IHC-P
Host:	Mouse
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality :	Monoclonal
Clone ID :	6F‐H2
Isotype:	IgG1k
Conjugation:	Unconjugated
Purification:	Affinity purified
Dilution Range:	1:100‐200
Formulation:	Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Storage Instruction:	Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C.

Gene Symbol:	WT1
Gene ID:	7490
Uniprot ID:	WT1_HUMAN
Immunogen:	Purified WT protein
Specificity:	Positive control: Malignant mesothelioma

Tissue Specificity	Expressed in the kidney and a subset of hematopoietic cells.
Function	Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.
Protein Name	Wilms Tumor Protein Wt33
Database Links	Reactome: R-HSA-9690406 Reactome: R-HSA-9831926
Cellular Localisation	Nucleus Nucleolus Cytoplasm Isoforms Lacking The Kts Motif Have A Diffuse Nuclear Location Shuttles Between Nucleus And Cytoplasm Isoform 1: Nucleus Speckle Isoform 4: Nucleus Nucleoplasm
Alternative Antibody Names	Anti-Wilms Tumor Protein antibody Anti-Wt33 antibody Anti-WT1 antibody

Information sourced from Uniprot.org

Anti-WT1 antibody [6F‐H2] (STJ180267)

General Information

Model	Name	Host	Clonality	Reactivity	Application
STJ16100439	Anti-WT1 antibody [6F-H2] (STJ16100439)	Mouse	Monoclonal	Human	IHC-P
STJA0042067	Anti-WT1 antibody [IHC685] (STJA0042067)	Mouse	Monoclonal	Human	IHC-p
STJ196897	Anti-WT1 antibody (350-449 aa) [ABT-WT1] (STJ196897)	Mouse	Monoclonal	Human/Mouse/Rat	IHC/WB/IF
STJ11109805	Anti-WT1 antibody [SRM15075] (STJ11109805)	Rabbit	Monoclonal	Human	WB/ELISA
STJA0027348	Anti-CD7 antibody [WT1] (STJA0027348)	Mouse	Monoclonal	Human	FC