| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | WNT9A |
| Gene ID: | 7483 |
| Uniprot ID: | WNT9A_HUMAN |
| Immunogen Region: | 250-350 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 250-350 of human WNT9A (NP_003386.1). |
| Immunogen Sequence: | ALKVGSTTNEAAGEAGAISP PRGRASGAGGSDPLPRTPEL VHLDDSPSFCLAGRFSPGTA GRRCHREKNCESICCGRGHN TQSRVVTRPCQCQVRWCCYV E |
| Post Translational Modifications | Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition. |
| Function | Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal timing of IHH expression during embryonic bone development, normal chondrocyte maturation and for normal bone mineralization during embryonic bone development. Plays a redundant role in maintaining joint integrity. |
| Protein Name | Protein Wnt-9aProtein Wnt-14 |
| Database Links | Reactome: R-HSA-201681Reactome: R-HSA-3238698Reactome: R-HSA-373080Reactome: R-HSA-3772470 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Protein Wnt-9a antibodyAnti-Protein Wnt-14 antibodyAnti-WNT9A antibodyAnti-WNT14 antibody |
Information sourced from Uniprot.org