![Anti-Wilms NA Tumor antibody [WT49] (STJ16101804)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/152310/347157/STJ16101804_1__72304.1681999432.jpg?c=1 "Anti-Wilms NA Tumor antibody [WT49] (STJ16101804)")
![Anti-Wilms NA Tumor antibody [WT49] (STJ16101804)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/152310/347157/STJ16101804_1__72304.1681999432.jpg?c=1 "Anti-Wilms NA Tumor antibody [WT49] (STJ16101804)")
| Host: | Mouse |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Wilms Tumor is suitable for use in Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | WT49 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | Tissue culture supernatant with sodium azide |
| Concentration: | >=44 mg/L |
| Dilution Range: | IHC-P 1:100 |
| Storage Instruction: | Store at 2-8°C upon receipt. |
| Immunogen: | A prokaryotic recombinant protein containing 1–181 amino acids of the N-terminal of the Wilms Tumor protein. |
| Background | Wilms tumor protein (WT1) has a role in transcriptional regulation and is expressed in the kidney and a subset of hematopoietic cells. Alteration of transcription factor function is a common mechanism in oncogenesis. The WT1 protein contains a DNA binding domain and any deletions or point mutations of the WT1 gene which destroy this activity result in the development of the childhood nephroblastoma Wilms tumor and Denys-Drash syndrome. The description of WT1 involvement in nephroblastoma is not clear. |
Information sourced from Uniprot.org