• Immunofluorescence analysis of U2OS cells using WDR46 Rabbit polyclonal antibody (STJ11103980) at dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of PC-12 cells using WDR46 Rabbit polyclonal antibody (STJ11103980) at dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of NIH/3T3 cells using WDR46 Rabbit polyclonal antibody (STJ11103980) at dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.
  • Immunohistochemistry analysis of paraffin-embedded human esophagus using WDR46 Rabbit polyclonal antibody (STJ11103980) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded human colon carcinoma using WDR46 Rabbit polyclonal antibody (STJ11103980) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.

Anti-WDR46 antibody (421-610) (STJ11103980)

SKU:
STJ11103980

£112.50 - £522.50
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Wd Repeat-Containing Protein 46 (421-610) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC-P 1:50-1:200
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: WDR46
Gene ID: 9277
Uniprot ID: WDR46_HUMAN
Immunogen Region: 421-610
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 421-610 of human WDR46 (NP_005443.3).
Immunogen Sequence: DVVNIWAGQGKASPPSLEQP YLTHRLSGPVHGLQFCPFED VLGVGHTGGITSMLVPGAGE PNFDGLESNPYRSRKQRQEW EVKALLEKVPAELICLDPRA LAEVDVISLEQGKKEQIERL GYDPQAKAPFQPKPKQKGRS STASLVKRKRKVMDEEHRDK VRQSLQQQHHKEAKAKPTGA RPSALDRFVR
Function Scaffold component of the nucleolar structure. Required for localization of DDX21 and NCL to the granular compartment of the nucleolus. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
Protein Name Wd Repeat-Containing Protein 46
Wd Repeat-Containing Protein Bing4
Database Links Reactome: R-HSA-6790901
Reactome: R-HSA-6791226
Cellular Localisation Nucleus
Nucleolus
Alternative Antibody Names Anti-Wd Repeat-Containing Protein 46 antibody
Anti-Wd Repeat-Containing Protein Bing4 antibody
Anti-WDR46 antibody
Anti-BING4 antibody
Anti-C6orf11 antibody
Anti-FP221 antibody

Information sourced from Uniprot.org

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