Tissue Specificity | Ubiquitous. Highly expressed in the heart, pancreas, kidney skeletal muscle, placenta and brain (at protein level). Weakly expressed in liver and lung. |
Function | Activates pre-mRNA splicing. May inhibit PP1 phosphatase activity. |
Protein Name | Ww Domain-Binding Protein 11Wbp-11Npw38-Binding ProteinNpwbpSh3 Domain-Binding Protein Snp70Splicing Factor That Interacts With Pqbp-1 And Pp1 |
Database Links | Reactome: R-HSA-72163 |
Cellular Localisation | NucleusCytoplasmPredominantly Located In The Nucleus With Granular Heterogeneous DistributionExcluded From Nucleoli In Interphase CellsDistributed Throughout Cytoplasm In Dividing CellsColocalized With Sc35 And U2b In The NucleusIn The CytoplasmAssociates With The Intermediate Filament Protein Vimentin |
Alternative Antibody Names | Anti-Ww Domain-Binding Protein 11 antibodyAnti-Wbp-11 antibodyAnti-Npw38-Binding Protein antibodyAnti-Npwbp antibodyAnti-Sh3 Domain-Binding Protein Snp70 antibodyAnti-Splicing Factor That Interacts With Pqbp-1 And Pp1 antibodyAnti-WBP11 antibodyAnti-NPWBP antibodyAnti-SIPP1 antibodyAnti-SNP70 antibody |
Information sourced from Uniprot.org