Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Syndetin (177-227 aa) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
VPS50 |
Gene ID: |
55610 |
Uniprot ID: |
VPS50_HUMAN |
Immunogen Region: |
177-227 aa |
Specificity: |
This antibody detects endogenous levels of CC132 at Human/Mouse |
Immunogen: |
Synthesized peptide derived from the human CC132 at the amino acid range 177-227 |
Function | Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane. Within the EARP complex, required to tether the complex to recycling endosomes. Not involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). |
Protein Name | SyndetinCoiled-Coil Domain-Containing Protein 132Earp/Garpii Complex Subunit Vps50 |
Cellular Localisation | Recycling EndosomeMembraneAssociates With Membranes In An Eipr1-Dependent Manner |
Alternative Antibody Names | Anti-Syndetin antibodyAnti-Coiled-Coil Domain-Containing Protein 132 antibodyAnti-Earp/Garpii Complex Subunit Vps50 antibodyAnti-VPS50 antibodyAnti-CCDC132 antibodyAnti-KIAA1861 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance