| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-VPS37C (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 38kDa band observed in human duodenum lysates (calculated MW of 38.7kDa according to NP_060436.4). Recommended concentration: 0.03-0.1µg/ml.IHC: Paraffin embedded Human Pro |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | VPS37C |
| Gene ID: | 55048 |
| Uniprot ID: | VP37C_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_060436.4 |
| Immunogen Sequence: | ETLKDKTLQELEELQ |
| Function | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. |
| Protein Name | Vacuolar Protein Sorting-Associated Protein 37cHvps37cEscrt-I Complex Subunit Vps37c |
| Database Links | Reactome: R-HSA-162588Reactome: R-HSA-174490Reactome: R-HSA-917729Reactome: R-HSA-9610379Reactome: R-HSA-9615710 |
| Cellular Localisation | Late Endosome MembranePeripheral Membrane ProteinProbably Associates With MembranesRecruited To The Plasma Membrane By Hiv-1 |
| Alternative Antibody Names | Anti-Vacuolar Protein Sorting-Associated Protein 37c antibodyAnti-Hvps37c antibodyAnti-Escrt-I Complex Subunit Vps37c antibodyAnti-VPS37C antibodyAnti-PML39 antibody |
Information sourced from Uniprot.org
