| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Vacuolar protein sorting-associated protein 37C (220-270 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
VPS37C |
| Gene ID: |
55048 |
| Uniprot ID: |
VP37C_HUMAN |
| Immunogen Region: |
220-270 aa |
| Specificity: |
This antibody detects endogenous levels of VP37C at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human VP37C at the amino acid range 220-270 |
| Function | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. |
| Protein Name | Vacuolar Protein Sorting-Associated Protein 37cHvps37cEscrt-I Complex Subunit Vps37c |
| Database Links | Reactome: R-HSA-162588Reactome: R-HSA-174490Reactome: R-HSA-917729Reactome: R-HSA-9610379Reactome: R-HSA-9615710 |
| Cellular Localisation | Late Endosome MembranePeripheral Membrane ProteinProbably Associates With MembranesRecruited To The Plasma Membrane By Hiv-1 |
| Alternative Antibody Names | Anti-Vacuolar Protein Sorting-Associated Protein 37c antibodyAnti-Hvps37c antibodyAnti-Escrt-I Complex Subunit Vps37c antibodyAnti-VPS37C antibodyAnti-PML39 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
