Anti-VPS37C antibody (220-270 aa) (STJ195116)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human VP37C at the amino acid range 220-270
General Information
| Short Description | Rabbit polyclonal anti-Vacuolar protein sorting-associated protein 37C (220-270 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | VPS37C |
| Gene ID | 55048 |
| Uniprot ID | VP37C_HUMAN |
| Immunogen | Synthesized peptide derived from the human VP37C at the amino acid range 220-270 |
| Immunogen Region | 220-270 aa |
| Specificity | This antibody detects endogenous levels of VP37C at Human/Mouse |
Additional Info
| Function | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. |
| Protein Name | Vacuolar Protein Sorting-Associated Protein 37cHvps37cEscrt-I Complex Subunit Vps37c |
| Database Links | Reactome: R-HSA-162588Reactome: R-HSA-174490Reactome: R-HSA-917729Reactome: R-HSA-9610379Reactome: R-HSA-9615710 |
| Cellular Localisation | Late Endosome MembranePeripheral Membrane ProteinProbably Associates With MembranesRecruited To The Plasma Membrane By Hiv-1 |
| Alternative Antibody Names | Anti-Vacuolar Protein Sorting-Associated Protein 37c antibodyAnti-Hvps37c antibodyAnti-Escrt-I Complex Subunit Vps37c antibodyAnti-VPS37C antibodyAnti-PML39 antibody |
Information sourced from Uniprot.org