Anti-VP33B antibody (C-Term) (STJ13100465)

SKU:
STJ13100465-100
$447.53
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: IHC/WB
Reactivity: Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-VP33B (C-Term) is suitable for use in Immunohistochemistry and Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Lyophilised
Purification: IgG purified
Dilution Range: IHC, WB. A dilution of 1: 200 to 1: 1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage Instruction: Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Gene Symbol: Vps33b
Gene ID: 64060
Uniprot ID: VP33B_RAT
Immunogen Region: C-Term
Specificity: Specific for VP33B.
Immunogen: A synthetic peptide from the c-terminal of rat VP33B conjugated to blue carrier protein was used as the antigen. The antigen shares 91% identity with mouse and human sequences.
Post Translational Modifications Phosphorylated on tyrosine residues.
Function May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages. Proposed to be involved in endosomal maturation implicating VIPAS39. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical recycling pathway and in the maintenance of the apical-basolateral polarity. Seems to be involved in the sorting of specific cargos from the trans-Golgi network to alpha-granule-destined multivesicular bodies (MVBs) promoting MVBs maturation in megakaryocytes.
Protein Name Vacuolar Protein Sorting-Associated Protein 33b
R-Vps33b
Cellular Localisation Late Endosome Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Lysosome Membrane
Early Endosome
Cytoplasmic Vesicle
Clathrin-Coated Vesicle
Recycling Endosome
Colocalizes In Clusters With Vipas39 At Cytoplasmic Organelles
Colocalizes With Rab11a And Vipas39 On Recycling Endosomes
Colocalizes With Ap-3
Clathrin
Rab5 And Rab7b
Alternative Antibody Names Anti-Vacuolar Protein Sorting-Associated Protein 33b antibody
Anti-R-Vps33b antibody
Anti-Vps33b antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ93953 Anti-LRG1 antibody (C-Term) (STJ93953) Rabbit Polyclonal Human/Rat/Mouse WB/ELISA/IHC
STJ94026 Anti-MASTL antibody (C-Term) (STJ94026) Rabbit Polyclonal Human/Rat/Mouse WB/ELISA
STJ96154 Anti-TBXAS1 antibody (C-Term) (STJ96154) Rabbit Polyclonal Human/Rat/Mouse WB/ELISA
STJ96782 Anti-SLC26A3 antibody (C-Term) (STJ96782) Rabbit Polyclonal Human/Mouse/Rat WB/ELISA
STJ96372 Anti-B4GALT1 antibody (C-Term) (STJ96372) Rabbit Polyclonal Human/Mouse WB/IHC/IF/ELISA
!