Vitamin D Binding Protein antibody western blot human plasma STJA0036303

Anti-Vitamin D Binding Protein antibody [R05-7E7] (STJA0036303)

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STJA0036303
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Short Description :Rabbit monoclonal anti-Vitamin D Binding Protein for use in WB, IHC-P, ICC, IF and FC in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC-P/ICC/IF/FC
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :R05-7E7
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity Chromatography
Dilution Range:WB 1:500-1:1000
IHC 1:50-1:100
IF 1:50-1:200
FC 1:50-1:100
Formulation:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:GC
Gene ID:2638
Uniprot ID:VTDB_HUMAN
Immunogen:A synthesized peptide derived from human GC/VDBP
Tissue Specificity Expressed in the liver. Found in plasma, ascites, cerebrospinal fluid and urine.
Post Translational Modifications Allele GC*1S is O-glycosylated at Thr-436. The trisaccharide sugar moiety can be modified by the successive removal of neuraminic acid and galactose leaving an O-mceeN-acetyl-galactosamine. This conversion is thought to produce a macrophage-activating factor (Gc-MAF). Only a minor proportion of plasma GC is O-glycosylated. The potential N-glycosylation site predicted at Asn-288 is thought to be nonglycosylated.
Function Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.
Protein Name Vitamin D-Binding Protein
Dbp
Vdb
Gc Protein-Derived Macrophage Activating Factor
Gc-Maf
Gcmaf
Gc-Globulin
Group-Specific Component
Gc
Vitamin D-Binding Protein-Macrophage Activating Factor
Dbp-Maf
Database Links Reactome: R-HSA-196791
Cellular Localisation Secreted
Alternative Antibody Names Anti-Vitamin D-Binding Protein antibody
Anti-Dbp antibody
Anti-Vdb antibody
Anti-Gc Protein-Derived Macrophage Activating Factor antibody
Anti-Gc-Maf antibody
Anti-Gcmaf antibody
Anti-Gc-Globulin antibody
Anti-Group-Specific Component antibody
Anti-Gc antibody
Anti-Vitamin D-Binding Protein-Macrophage Activating Factor antibody
Anti-Dbp-Maf antibody
Anti-GC antibody

Information sourced from Uniprot.org

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