| Function | Proposed to be involved in endosomal maturation implicating in part VPS33B. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical RAB11A-dependent recycling pathway and in the maintenance of the apical-basolateral polarity. May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes.the functions seems to be independent of VPS33B. May play a role in vesicular trafficking during spermatogenesis. May be involved in direct or indirect transcriptional regulation of E-cadherin. |
| Protein Name | Spermatogenesis-Defective Protein 39 HomologHspe-39Vps33b-Interacting Protein In Apical-Basolateral Polarity RegulatorVps33b-Interacting Protein In Polarity And Apical Restriction |
| Database Links | |
| Cellular Localisation | CytoplasmCytoplasmic VesicleEarly EndosomeRecycling EndosomeLate EndosomeColocalizes In Clusters With Vps33b At Cytoplasmic Organelles |
| Alternative Antibody Names | Anti-Spermatogenesis-Defective Protein 39 Homolog antibodyAnti-Hspe-39 antibodyAnti-Vps33b-Interacting Protein In Apical-Basolateral Polarity Regulator antibodyAnti-Vps33b-Interacting Protein In Polarity And Apical Restriction antibodyAnti-VIPAS39 antibodyAnti-C14orf133 antibodyAnti-SPE39 antibodyAnti-VIPAR antibody |
Information sourced from Uniprot.org
