| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | VEPH1 |
| Gene ID: | 79674 |
| Uniprot ID: | MELT_HUMAN |
| Immunogen Region: | 448-547 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 448-547 of human VEPH1 (NP_078897.2). |
| Immunogen Sequence: | KSLAFHTMLTKGVGSDDGED ENRGDIPASISLSEIDPLGQ GNDKLPFKTDTERSQLGESS VSYPNIIHIDSENLSETVKE NSQEETPETTASPIEYQDKL |
| Function | Interacts with TGF-beta receptor type-1 (TGFBR1) and inhibits dissociation of activated SMAD2 from TGFBR1, impeding its nuclear accumulation and resulting in impaired TGF-beta signaling. May also affect FOXO, Hippo and Wnt signaling. |
| Protein Name | Ventricular Zone-Expressed Ph Domain-Containing Protein Homolog 1Protein Melted |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Ventricular Zone-Expressed Ph Domain-Containing Protein Homolog 1 antibodyAnti-Protein Melted antibodyAnti-VEPH1 antibodyAnti-KIAA1692 antibodyAnti-VEPH antibody |
Information sourced from Uniprot.org