• Western blot analysis of various lysates using UTP18 Rabbit polyclonal antibody (STJ117636) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-UTP18 antibody (70-260) (STJ117636)

SKU:
STJ117636

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-UTP18 (70-260) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: UTP18
Gene ID: 51096
Uniprot ID: UTP18_HUMAN
Immunogen Region: 70-260
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 70-260 of human UTP18 (NP_057085.2).
Immunogen Sequence: RRLRQRNRLRLEEDKPAVER CLEELVFGDVENDEDALLRR LRGPRVQEHEDSGDSEVENE AKGNFPPQKKPVWVDEEDED EEMVDMMNNRFRKDMMKNAS ESKLSKDNLKKRLKEEFQHA MGGVPAWAETTKRKTSSDDE SEEDEDDLLQRTGNFISTST SLPRGILKMKNCQHANAERP TVARISSVQFH
Function Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA.
Protein Name U3 Small Nucleolar Rna-Associated Protein 18 Homolog
Wd Repeat-Containing Protein 50
Database Links Reactome: R-HSA-6790901
Reactome: R-HSA-6791226
Cellular Localisation Nucleus
Nucleolus
Alternative Antibody Names Anti-U3 Small Nucleolar Rna-Associated Protein 18 Homolog antibody
Anti-Wd Repeat-Containing Protein 50 antibody
Anti-UTP18 antibody
Anti-WDR50 antibody
Anti-CDABP0061 antibody
Anti-CGI-48 antibody

Information sourced from Uniprot.org

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