| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Ubiquitin carboxyl-terminal hydrolase 45 (301-350 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | USP45 |
| Gene ID: | 85015 |
| Uniprot ID: | UBP45_HUMAN |
| Immunogen Region: | 301-350 aa |
| Specificity: | USP45 Polyclonal Antibody detects endogenous levels of USP45 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human USP45 at the amino acid range 301-350 |
| Function | Catalyzes the deubiquitination of SPDL1. Plays a role in the repair of UV-induced DNA damage via deubiquitination of ERCC1, promoting its recruitment to DNA damage sites. May be involved in the maintenance of photoreceptor function. May play a role in normal retinal development. Plays a role in cell migration. |
| Protein Name | Ubiquitin Carboxyl-Terminal Hydrolase 45Deubiquitinating Enzyme 45Ubiquitin Thioesterase 45Ubiquitin-Specific-Processing Protease 45 |
| Database Links | Reactome: R-HSA-5696395 |
| Cellular Localisation | Photoreceptor Inner SegmentCytoplasmNucleus |
| Alternative Antibody Names | Anti-Ubiquitin Carboxyl-Terminal Hydrolase 45 antibodyAnti-Deubiquitinating Enzyme 45 antibodyAnti-Ubiquitin Thioesterase 45 antibodyAnti-Ubiquitin-Specific-Processing Protease 45 antibodyAnti-USP45 antibody |
Information sourced from Uniprot.org