| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Ubiquitin carboxyl-terminal hydrolase 45 (301-350 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000ELISA 1:10000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
USP45 |
| Gene ID: |
85015 |
| Uniprot ID: |
UBP45_HUMAN |
| Immunogen Region: |
301-350 aa |
| Specificity: |
USP45 Polyclonal Antibody detects endogenous levels of USP45 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human USP45 at the amino acid range 301-350 |
| Function | Catalyzes the deubiquitination of SPDL1. Plays a role in the repair of UV-induced DNA damage via deubiquitination of ERCC1, promoting its recruitment to DNA damage sites. May be involved in the maintenance of photoreceptor function. May play a role in normal retinal development. Plays a role in cell migration. |
| Protein Name | Ubiquitin Carboxyl-Terminal Hydrolase 45Deubiquitinating Enzyme 45Ubiquitin Thioesterase 45Ubiquitin-Specific-Processing Protease 45 |
| Database Links | Reactome: R-HSA-5696395 |
| Cellular Localisation | Photoreceptor Inner SegmentCytoplasmNucleus |
| Alternative Antibody Names | Anti-Ubiquitin Carboxyl-Terminal Hydrolase 45 antibodyAnti-Deubiquitinating Enzyme 45 antibodyAnti-Ubiquitin Thioesterase 45 antibodyAnti-Ubiquitin-Specific-Processing Protease 45 antibodyAnti-USP45 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
