Anti-USP24 antibody (2431-2620) (STJ112599)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal USP24 (2431-2620) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | USP24 |
| Gene ID | 23358 |
| Uniprot ID | UBP24_HUMAN |
| Immunogen Region | 2431-2620 |
| Immunogen Sequence | FTMLHFIKNQLETAPPHELK NTFQLLHEILVIEDPIQVER VKFVFETENGLLALMHHSNH VDSSRCYQCVKFLVTLAQKC PAAKEYFKENSHHWSWAVQW LQKKMSEHYWTPQSNVSNET STGKTFQRTISAQDTLAYAT ALLNEKEQSGSSNGSESSPA NENGDRHLQQGSESPMMIGE LRSDLDDVDP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 2431-2620 of human USP24 (NP_056121.2). |
Additional Info
| Function | Ubiquitin-specific protease that regulates cell survival in various contexts through modulating the protein stability of some of its substrates including DDB2, MCL1 or TP53. Plays a positive role on ferritinophagy where ferritin is degraded in lysosomes and releases free iron. |
| Protein Name | Ubiquitin Carboxyl-Terminal Hydrolase 24Deubiquitinating Enzyme 24Ubiquitin Thioesterase 24Ubiquitin-Specific-Processing Protease 24 |
| Database Links | Reactome: R-HSA-5689880 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Ubiquitin Carboxyl-Terminal Hydrolase 24 antibodyAnti-Deubiquitinating Enzyme 24 antibodyAnti-Ubiquitin Thioesterase 24 antibodyAnti-Ubiquitin-Specific-Processing Protease 24 antibodyAnti-USP24 antibodyAnti-KIAA1057 antibody |
Information sourced from Uniprot.org