Anti-UROS antibody (25-75 aa) (STJ194087)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human HEM4 at the amino acid range 25-75
General Information
| Short Description | Rabbit polyclonal anti-Uroporphyrinogen-III synthase (25-75 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Mgu |
| Gene ID | 7390 |
| Uniprot ID | HEM4_HUMAN |
| Immunogen | Synthesized peptide derived from the human HEM4 at the amino acid range 25-75 |
| Immunogen Region | 25-75 aa |
| Specificity | This antibody detects endogenous levels of HEM4 at Human/Mouse |
Additional Info
| Function | Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme). |
| Protein Name | Uroporphyrinogen-Iii SynthaseUroiiisUrosHydroxymethylbilane Hydrolyase CyclizingUroporphyrinogen-Iii Cosynthase |
| Database Links | Reactome: R-HSA-189451 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Uroporphyrinogen-Iii Synthase antibodyAnti-Uroiiis antibodyAnti-Uros antibodyAnti-Hydroxymethylbilane Hydrolyase Cyclizing antibodyAnti-Uroporphyrinogen-Iii Cosynthase antibodyAnti-Mgu antibodyAnti-UROS antibody |
Information sourced from Uniprot.org