Anti-UPB1 antibody (1-240) (STJ117647)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal UPB1 (1-240) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UPB1 |
| Gene ID | 51733 |
| Uniprot ID | BUP1_HUMAN |
| Immunogen Region | 1-240 |
| Immunogen Sequence | MAGAEWKSLEECLEKHLPLP DLQEVKRVLYGKELRKLDLP REAFEAASREDFELQGYAFE AAEEQLRRPRIVHVGLVQNR IPLPANAPVAEQVSALHRRI KAIVEVAAMCGVNIICFQEA WTMPFAFCTREKLPWTEFAE SAEDGPTTRFCQKLAKNHDM VVVSPILERDSEHGDVLWNT AVVISNSGAVLGKTRKNHIP RVGDFNESTYYMEGNLGHPV FQTQFGRIAVNICYGRHHP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human UPB1 (NP_057411.1). |
Additional Info
| Tissue Specificity | Detected in liver (at protein level). |
| Function | Catalyzes a late step in pyrimidine degradation. Converts N-carbamoyl-beta-alanine (3-ureidopropanoate) into beta-alanine, ammonia and carbon dioxide. Likewise, converts N-carbamoyl-beta-aminoisobutyrate (3-ureidoisobutyrate) into beta-aminoisobutyrate, ammonia and carbon dioxide (Probable). |
| Protein Name | Beta-UreidopropionaseBup-1Beta-Alanine SynthaseN-Carbamoyl-Beta-Alanine Amidohydrolase |
| Database Links | Reactome: R-HSA-73621 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Beta-Ureidopropionase antibodyAnti-Bup-1 antibodyAnti-Beta-Alanine Synthase antibodyAnti-N-Carbamoyl-Beta-Alanine Amidohydrolase antibodyAnti-UPB1 antibodyAnti-BUP1 antibody |
Information sourced from Uniprot.org