Tissue Specificity | Expressed in various tissues including the liver, kidney, testis, uterus, placenta, mammary gland, adrenal gland, skin and prostate. |
Function | UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile. Catalyzes the glucuronidation of endogenous steroid hormones such as androgens (epitestosterone, androsterone) and estrogens (estradiol, epiestradiol). |
Protein Name | Udp-Glucuronosyltransferase 2b17Udpgt 2b17Ugt2b17C19-Steroid-Specific Udp-GlucuronosyltransferaseC19-Steroid-Specific Udpgt |
Database Links | Reactome: R-HSA-156588Reactome: R-HSA-9749641Reactome: R-HSA-9757110 |
Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane Protein |
Alternative Antibody Names | Anti-Udp-Glucuronosyltransferase 2b17 antibodyAnti-Udpgt 2b17 antibodyAnti-Ugt2b17 antibodyAnti-C19-Steroid-Specific Udp-Glucuronosyltransferase antibodyAnti-C19-Steroid-Specific Udpgt antibodyAnti-UGT2B17 antibody |
Information sourced from Uniprot.org