| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Putative mitochondrial transporter UCP3 (259-308 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000ELISA 1:10000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
UCP3 |
| Gene ID: |
7352 |
| Uniprot ID: |
UCP3_HUMAN |
| Immunogen Region: |
259-308 aa |
| Specificity: |
UCP3 Polyclonal Antibody detects endogenous levels of UCP3 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human UCP3 at the amino acid range 259-308 |
| Function | Putative transmembrane transporter that plays a role in mitochondrial metabolism via an as yet unclear mechanism. Originally, this mitochondrial protein was thought to act as a proton transmembrane transporter from the mitochondrial intermembrane space into the matrix, causing proton leaks through the inner mitochondrial membrane, thereby uncoupling mitochondrial membrane potential generation from ATP synthesis. However, this function is controversial and uncoupling may not be the function, or at least not the main function, but rather a consequence of more conventional metabolite transporter activity. |
| Protein Name | Putative Mitochondrial Transporter Ucp3Solute Carrier Family 25 Member 9Uncoupling Protein-3Ucp 3 |
| Database Links | Reactome: R-HSA-167826Reactome: R-HSA-167827 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Putative Mitochondrial Transporter Ucp3 antibodyAnti-Solute Carrier Family 25 Member 9 antibodyAnti-Uncoupling Protein-3 antibodyAnti-Ucp 3 antibodyAnti-UCP3 antibodyAnti-SLC25A9 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
