| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | UBE2R2 |
| Gene ID: | 54926 |
| Uniprot ID: | UB2R2_HUMAN |
| Immunogen Region: | 1-238 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-238 of human UBE2R2 (NP_060281.2). |
| Immunogen Sequence: | MAQQQMTSSQKALMLELKSL QEEPVEGFRITLVDESDLYN WEVAIFGPPNTLYEGGYFKA HIKFPIDYPYSPPTFRFLTK MWHPNIYENGDVCISILHPP VDDPQSGELPSERWNPTQNV RTILLSVISLLNEPNTFSPA NVDASVMFRKWRDSKGKDKE YAEIIRKQVSATKAEAEKDG VKVPTTLAEYCIKTKVPSND NSSDLLYDDLYDDDIDDEDE EEEDADCYDDDDSGNEES |
| Function | E2 ubiquitin-conjugating enzyme that accepts ubiquitin from an E1 ubiquitin-activating protein, and catalyzes its covalent attachment to other proteins by an E3 ubiquitin-protein ligase complex. In vitro catalyzes monoubiquitination and 'Lys-48'-linked polyubiquitination. Works in collaboration with various Cul1-RING and Cul2-RING E3 ligase complexes. May be involved in degradation of katenin. |
| Protein Name | Ubiquitin-Conjugating Enzyme E2 R2E2 Ubiquitin-Conjugating Enzyme R2Ubiquitin Carrier Protein R2Ubiquitin-Conjugating Enzyme E2-Cdc34bUbiquitin-Protein Ligase R2 |
| Database Links | Reactome: R-HSA-8866652Reactome: R-HSA-983168 |
| Alternative Antibody Names | Anti-Ubiquitin-Conjugating Enzyme E2 R2 antibodyAnti-E2 Ubiquitin-Conjugating Enzyme R2 antibodyAnti-Ubiquitin Carrier Protein R2 antibodyAnti-Ubiquitin-Conjugating Enzyme E2-Cdc34b antibodyAnti-Ubiquitin-Protein Ligase R2 antibodyAnti-UBE2R2 antibodyAnti-CDC34B antibodyAnti-UBC3B antibody |
Information sourced from Uniprot.org