Anti-UBE2R2 antibody (1-238) (STJ29510)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal UBE2R2 (1-238) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | UBE2R2 |
| Gene ID | 54926 |
| Uniprot ID | UB2R2_HUMAN |
| Immunogen Region | 1-238 |
| Immunogen Sequence | MAQQQMTSSQKALMLELKSL QEEPVEGFRITLVDESDLYN WEVAIFGPPNTLYEGGYFKA HIKFPIDYPYSPPTFRFLTK MWHPNIYENGDVCISILHPP VDDPQSGELPSERWNPTQNV RTILLSVISLLNEPNTFSPA NVDASVMFRKWRDSKGKDKE YAEIIRKQVSATKAEAEKDG VKVPTTLAEYCIKTKVPSND NSSDLLYDDLYDDDIDDEDE EEEDADCYDDDDSGNEES |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-238 of human UBE2R2 (NP_060281.2). |
Additional Info
| Function | E2 ubiquitin-conjugating enzyme that accepts ubiquitin from an E1 ubiquitin-activating protein, and catalyzes its covalent attachment to other proteins by an E3 ubiquitin-protein ligase complex. In vitro catalyzes monoubiquitination and 'Lys-48'-linked polyubiquitination. Works in collaboration with various Cul1-RING and Cul2-RING E3 ligase complexes. May be involved in degradation of katenin. |
| Protein Name | Ubiquitin-Conjugating Enzyme E2 R2E2 Ubiquitin-Conjugating Enzyme R2Ubiquitin Carrier Protein R2Ubiquitin-Conjugating Enzyme E2-Cdc34bUbiquitin-Protein Ligase R2 |
| Database Links | Reactome: R-HSA-8866652Reactome: R-HSA-983168 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Ubiquitin-Conjugating Enzyme E2 R2 antibodyAnti-E2 Ubiquitin-Conjugating Enzyme R2 antibodyAnti-Ubiquitin Carrier Protein R2 antibodyAnti-Ubiquitin-Conjugating Enzyme E2-Cdc34b antibodyAnti-Ubiquitin-Protein Ligase R2 antibodyAnti-UBE2R2 antibodyAnti-CDC34B antibodyAnti-UBC3B antibody |
Information sourced from Uniprot.org