| Host: |
Goat |
| Applications: |
Pep-ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-TXNDC3 (Internal) is suitable for use in ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
Peptide ELISA: antibody detection limit dilution 1:16000.WB: Preliminary experiments in Human Testis lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
NME8 |
| Gene ID: |
51314 |
| Uniprot ID: |
TXND3_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_057700.3 |
| Immunogen Sequence: |
TEPQTDTEPNERSE |
| Function | Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. In vitro, it has neither nucleoside diphosphate kinase (NDPK) activity nor reducing activity on disulfide bonds. Exhibits a 3'-5' exonuclease activity with a preference for single-stranded DNA, suggesting roles in DNA proofreading and repair. |
| Protein Name | Thioredoxin Domain-Containing Protein 33'-5' Exonuclease Nme8Nm23-H8Nme/Nm23 Family Member 8Spermatid-Specific Thioredoxin-2Sptrx-2 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Thioredoxin Domain-Containing Protein 3 antibodyAnti-3'-5' Exonuclease Nme8 antibodyAnti-Nm23-H8 antibodyAnti-Nme/Nm23 Family Member 8 antibodyAnti-Spermatid-Specific Thioredoxin-2 antibodyAnti-Sptrx-2 antibodyAnti-NME8 antibodyAnti-SPTRX2 antibodyAnti-TXNDC3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
