| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TXN2 |
| Gene ID: | 25828 |
| Uniprot ID: | THIOM_HUMAN |
| Immunogen Region: | 1-166 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human Thioredoxin 2 (Trx2/Thioredoxin 2 (Trx2/TXN2) ) (NP_036605.2). |
| Immunogen Sequence: | MAQRLLLRRFLASVISRKPS QGQWPPLTSRALQTPQCSPG GLTVTPNPARTIYTTRISLT TFNIQDGPDFQDRVVNSETP VVVDFHAQWCGPCKILGPRL EKMVAKQHGKVVMAKVDIDD HTDLAIEYEVSAVPTVLAMK NGDVVDKFVGIKDEDQLEAF LKKLIG |
| Tissue Specificity | Widely expressed in adult (at protein level) and fetal tissues. |
| Function | Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability Is involved in various redox reactions including the reduction of protein disulfide bonds, through the reversible oxidation of its active center dithiol to a disulfide. |
| Protein Name | Thioredoxin - MitochondrialMtrxMt-TrxThioredoxin-2 |
| Database Links | Reactome: R-HSA-1614558Reactome: R-HSA-3299685 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Thioredoxin - Mitochondrial antibodyAnti-Mtrx antibodyAnti-Mt-Trx antibodyAnti-Thioredoxin-2 antibodyAnti-TXN2 antibodyAnti-TRX2 antibody |
Information sourced from Uniprot.org
