| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TUSC2 |
| Gene ID: | 11334 |
| Uniprot ID: | TUSC2_HUMAN |
| Immunogen Region: | 1-110 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human TUSC2 (NP_009206.1). |
| Immunogen Sequence: | MGASGSKARGLWPFASAAGG GGSEAAGAEQALVRPRGRAV PPFVFTRRGSMFYDEDGDLA HEFYEETIVTKNGQKRAKLR RVHKNLIPQGIVKLDHPRIH VDFPVILYEV |
| Tissue Specificity | Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta. |
| Post Translational Modifications | Myristoylation is required for tumor suppressor activity. |
| Function | May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells. |
| Protein Name | Tumor Suppressor Candidate 2Fusion 1 ProteinFus-1 ProteinPdgfa-Associated Protein 2 |
| Alternative Antibody Names | Anti-Tumor Suppressor Candidate 2 antibodyAnti-Fusion 1 Protein antibodyAnti-Fus-1 Protein antibodyAnti-Pdgfa-Associated Protein 2 antibodyAnti-TUSC2 antibodyAnti-C3orf11 antibodyAnti-FUS1 antibodyAnti-LGCC antibodyAnti-PDAP2 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and TXNDC9 knockout (KO) HeLa cells, using [KO Validated] TXNDC9 Rabbit polyclonal antibody (STJ11100745) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89683/358174/STJ11100745_1__65395.1713122481.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and TXNDC9 knockout (KO) HeLa cells, using [KO Validated] TXNDC9 Rabbit polyclonal antibody (STJ11100745) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
