| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TTF2 |
| Gene ID: | 8458 |
| Uniprot ID: | TTF2_HUMAN |
| Immunogen Region: | 1-270 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human TTF2 (NP_003585.3). |
| Immunogen Sequence: | MEEVRCPEHGTFCFLKTGVR DGPNKGKSFYVCRADTCSFV RATDIPVSHCLLHEDFVVEL QGLLLPQDKKEYRLFFRCIR SKAEGKRWCGSIPWQDPDSK EHSVSNKSQHASETFHHSSN WLRNPFKVLDKNQEPALWKQ LIKGEGEEKKADKKQREKGD QLFDQKKEQKPEMMEKDLSS GLVPKKKQSVVQEKKQEEGA EIQCEAETGGTHKRDFSEIK SQQCQGNELTRPSASSQEK |
| Function | DsDNA-dependent ATPase which acts as a transcription termination factor by coupling ATP hydrolysis with removal of RNA polymerase II from the DNA template. May contribute to mitotic transcription repression. May also be involved in pre-mRNA splicing. |
| Protein Name | Transcription Termination Factor 2Lodestar HomologRna Polymerase Ii Termination FactorTranscription Release Factor 2F2Huf2 |
| Cellular Localisation | CytoplasmNucleusCytoplasmic During InterphaseRelocates To The Nucleus As Cells Enter Mitosis |
| Alternative Antibody Names | Anti-Transcription Termination Factor 2 antibodyAnti-Lodestar Homolog antibodyAnti-Rna Polymerase Ii Termination Factor antibodyAnti-Transcription Release Factor 2 antibodyAnti-F2 antibodyAnti-Huf2 antibodyAnti-TTF2 antibody |
Information sourced from Uniprot.org