| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TTC7A |
| Gene ID: | 57217 |
| Uniprot ID: | TTC7A_HUMAN |
| Immunogen Region: | 1-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TTC7A (NP_001275880.1). |
| Immunogen Sequence: | MAAKGAHGSYLKVESELERC RAEGHWDRMPELVRQLQTLS MPGGGGNRRGSPSAAFTFPD TDDFGKLLLAEALLEQCLKE NHAKIKDSMPLLEKNEPKMS EAKNYLSSILNHGRLSPQYM CEAMLILGKLHYVEGSYRDA ISMYARAGIDDMSMENKPLY QMRLLSEAFVIKGLSLERLP NSIASRFRLTEREEEVITCF ERASWIAQVFLQELEKTTNN STSRHLKGCHPLDYELTYF |
| Tissue Specificity | Expressed in epithelial cells of the intestine, thymus, and pancreas (at protein level). |
| Function | Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (Probable). In the complex, plays a central role in bridging PI4KA to EFR3B and HYCC1, via direct interactions. |
| Protein Name | Tetratricopeptide Repeat Protein 7aTpr Repeat Protein 7a |
| Database Links | |
| Cellular Localisation | CytoplasmCell MembraneLocalizes To The Cytosol And Is Recruited To The Plasma Membrane Following Interaction With Efr3 (Efr3a Or Efr3b) |
| Alternative Antibody Names | Anti-Tetratricopeptide Repeat Protein 7a antibodyAnti-Tpr Repeat Protein 7a antibodyAnti-TTC7A antibodyAnti-KIAA1140 antibodyAnti-TTC7 antibody |
Information sourced from Uniprot.org
