| Host: | Rabbit |
| Applications: | WB/IHC-P/IP |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-Tryptophan 5 Hydroxylase 1 for use in WB, IHC-P and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | R06-2J1 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification: | Affinity Chromatography |
| Dilution Range: | WB 1:500-1:1000IHC 1:50-1:100IP 1:50 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | TPH1 |
| Gene ID: | 7166 |
| Uniprot ID: | TPH1_HUMAN |
| Immunogen: | A synthesized peptide derived from human TPH1 |
| Tissue Specificity | Isoform 2: Seems to be less widely expressed than isoform 1. |
| Post Translational Modifications | Ubiquitinated, leading to its degradation by the proteasome. Ubiquitinated is triggered by phosphorylation. Phosphorylated.triggering degradation by the proteasome. |
| Function | Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis. |
| Protein Name | Tryptophan 5-Hydroxylase 1Tryptophan 5-Monooxygenase 1 |
| Database Links | Reactome: R-HSA-209931Reactome: R-HSA-9031628 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Tryptophan 5-Hydroxylase 1 antibodyAnti-Tryptophan 5-Monooxygenase 1 antibodyAnti-TPH1 antibodyAnti-TPH antibodyAnti-TPRH antibodyAnti-TRPH antibody |
Information sourced from Uniprot.org
