| Host: | Mouse |
| Applications: | FIA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-Trypsinogen-2 for use in FIA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | 8607 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | 50 mM citrate, pH 7.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Concentration: | 5.0 mg/ml (+/-10 %) |
| Storage Instruction: | Store at 2–8 °C, and do not freeze. |
| Specificity: | Antibody recognizes human trypsinogen-2. Human Trypsin-1 2 %, Human Trypsin-2 6 % |
| Immunogen: | Not determined |
| Background | Trypsinogen is the precursor form of the pancreatic enzyme trypsin. It is found in pancreatic juice, along with amylase, lipase, and chymotrypsinogen. It is activated by enteropeptidase, which is found in the intestinal mucosa, to form trypsin. Once activated, the trypsin can activate more trypsinogen into trypsin. Trypsin cleaves peptide bond on carboxyl side of basic amino acids. High serum trypsinogen levels are seen in acute pancreatitis, and cystic fibrosis. Determination of urine trypsinogen-2 is also a useful test to detect acute pancreatitis and to evaluate disease severity. |
Information sourced from Uniprot.org
