• Immunohistochemical analysis of paraffin-embedded human-colon, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-colon, antibody was diluted at 1:100
  • Western blot analysis of extracts from Jurkat cells, using TRPV3 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-TRPV3 antibody (Internal) (STJ96460)

SKU:
STJ96460

£48.00 - £252.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Transient receptor potential cation channel subfamily V member 3 (Internal) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TRPV3
Gene ID: 162514
Uniprot ID: TRPV3_HUMAN
Immunogen Region: Internal
Specificity: TRPV3 Polyclonal Antibody detects endogenous levels of TRPV3 protein.
Immunogen: Synthesized peptide derived from the Internal region of human TRPV3.
Function Receptor-activated non-selective calcium permeant cation channel. It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius. Activation exhibits an outward rectification. May associate with TRPV1 and may modulate its activity. Is a negative regulator of hair growth and cycling: TRPV3-coupled signaling suppresses keratinocyte proliferation in hair follicles and induces apoptosis and premature hair follicle regression (catagen).
Protein Name Transient Receptor Potential Cation Channel Subfamily V Member 3
Trpv3
Vanilloid Receptor-Like 3
Vrl-3
Database Links Reactome: R-HSA-3295583
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cytoplasm
Lysosome
Targeted To Lysosome For Degradation In A Snx11-Dependent Manner
Alternative Antibody Names Anti-Transient Receptor Potential Cation Channel Subfamily V Member 3 antibody
Anti-Trpv3 antibody
Anti-Vanilloid Receptor-Like 3 antibody
Anti-Vrl-3 antibody
Anti-TRPV3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance