| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-Troponin I1/TnI1 (1-187) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S3MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TNNI1 |
| Gene ID: |
7135 |
| Uniprot ID: |
TNNI1_HUMAN |
| Immunogen Region: |
1-187 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-187 of human Troponin I1/TnI1 (P19237). |
| Immunogen Sequence: |
MPEVERKPKITASRKLLLKS LMLAKAKECWEQEHEEREAE KVRYLAERIPTLQTRGLSLS ALQDLCRELHAKVEVVDEER YDIEAKCLHNTREIKDLKLK VMDLRGKFKRPPLRRVRVSA DAMLRALLGSKHKVSMDLRA NLKSVKKEDTEKERPVEVGD WRKNVEAMSGMEGRKKMFDA AKSPTSQ |
| Tissue Specificity | Highest levels observed in human skeletal muscle (e.g. gastrocnemious muscle), differentiated cultures of primary human muscle cells and rhabdomyosarcoma cells cultured in low serum medium. Expressed in C2 muscle cell myoblasts and myotubes. |
| Function | Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. |
| Protein Name | Troponin I - Slow Skeletal MuscleTroponin I - Slow-Twitch Isoform |
| Database Links | Reactome: R-HSA-390522 |
| Alternative Antibody Names | Anti-Troponin I - Slow Skeletal Muscle antibodyAnti-Troponin I - Slow-Twitch Isoform antibodyAnti-TNNI1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
