| Short Description : | Rabbit polyclonal anti-Mitochondrial tRNA-specific 2-thiouridylase 1 (368-418 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TRMU |
| Gene ID: | 55687 |
| Uniprot ID: | MTU1_HUMAN |
| Immunogen: | Synthesized peptide derived from the human MTU1 at the amino acid range 368-418 |
| Immunogen Region: | 368-418 aa |
| Specificity: | This antibody detects endogenous levels of MTU1 at Human/Mouse/Rat |
| Function | Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base. |
| Protein Name | Mitochondrial Trna-Specific 2-Thiouridylase 1Mto2 Homolog |
| Database Links | Reactome: R-HSA-6787450 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Mitochondrial Trna-Specific 2-Thiouridylase 1 antibodyAnti-Mto2 Homolog antibodyAnti-TRMU antibodyAnti-MTU1 antibodyAnti-TRMT1 antibody |
Information sourced from Uniprot.org
