• STJ70350 (0. 5µg/ml) staining of Rat Brain (A) + Peptide (B) lysate (35µg protein in RIPA buffer). Detected by chemiluminescence.
  • STJ70350 Flow cytometric analysis of paraformaldehyde fixed Jurkat cells (blue line) , permeabilized with 0. 5% Triton. Primary incubation overnight (10ug/ml) followed by Alexa Fluor 488 secondary antibody (1ug/ml). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

Anti-TRIM2 antibody (C-Term) (STJ70350)

SKU:
STJ70350-100

£303.50
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Host: Goat
Applications: Pep-ELISA/WB/IHC/FC
Reactivity: Human/Mouse/Rat/Dog/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-TRIM2 (C-Term) is suitable for use in ELISA, Western Blot, Immunohistochemistry and Flow Cytometry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: IHC-6-12µg/ml
FC-Flow cytometric analysis of Jurkat cells. 10ug/ml
ELISA-antibody detection limit dilution 1:16000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: TRIM2
Gene ID: 23321
Uniprot ID: TRIM2_HUMAN
Immunogen Region: C-Term
Accession Number: NP_056086.2; NP_001123539.1; NP_001337983.1; NP_001337984.1; NP_001337985.1l; NP_001337986.1
Specificity: Cross-reactivity with TRIM3 has been demonstrated in Mouse.
Immunogen Sequence: DSGNHCFKVYRYLQ
Function UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance. Plays a role in antiviral immunity and limits New World arenavirus infection independently of its ubiquitin ligase activity.
Protein Name Tripartite Motif-Containing Protein 2
E3 Ubiquitin-Protein Ligase Trim2
Ring Finger Protein 86
Ring-Type E3 Ubiquitin Transferase Trim2
Database Links Reactome: R-HSA-877300
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Tripartite Motif-Containing Protein 2 antibody
Anti-E3 Ubiquitin-Protein Ligase Trim2 antibody
Anti-Ring Finger Protein 86 antibody
Anti-Ring-Type E3 Ubiquitin Transferase Trim2 antibody
Anti-TRIM2 antibody
Anti-KIAA0517 antibody
Anti-RNF86 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance